The Monoclonal Anti-Human PNMT Antibody (Clone AT1C11) from IBL- America is a Mouse Monoclonal antibody to phenylethanolamine N-methyltransferase, and PNMT. This antibody recognizes Homo Sapiens, and Human antigen. The Monoclonal Anti-Human PNMT Antibody (Clone AT1C11) has been validated for the following applications: EIA, Immunoassay, ELISA, and Western Blot.
Description
Phenylethanolamine N-methyltransferase (PNMT) catalyzes the synthesis of epinephrine and plays an important role in regulating cardiovascular function. Expression of PNMT is regulated by hormonal and neural stimuli because its promoter contains sequences responding to cholinergic and depolarization stimuli. PNMT is the final enzyme in the catecholamine pathway, catalyzing the conversion of norepinephrine to epinephrine using as the cosubstrate and methyl donor, S-adenosylmethionine